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Plans for the future of Lund Stem Cell Center

The leadership team set to guide Lund Stem Cell Center for the next three years was announced in early September 2020. In this interview with newly appointed coordinator Johan Jakobsson and deputy coordinator Johan Flygare, we hear about their future plans for this center of research excellence. What have been your first steps since taking over the reins at Lund Stem Cell Center? JJ: We have been

https://www.stemcellcenter.lu.se/article/plans-future-lund-stem-cell-center - 2025-12-08

Taking stem cells to high schools during the Covid-19 pandemic

Despite the ongoing pandemic, researchers from Lund Stem Cell Center are bringing science to schools both physically and using a digital platform. High school students across the Skåne region are learning about stem cell research in the ‘Taking science to schools – Borrow a scientist’ initiative, organized by the Research School in Stem Cell Biology.In this outreach project – planned for spring 20

https://www.stemcellcenter.lu.se/article/taking-stem-cells-high-schools-during-covid-19-pandemic - 2025-12-08

Restoring neural networks and understanding brain disorders

A research group from Lund Stem Cell Center aims to understand a specific type of neuron that could underlie several brain disorders including schizophrenia, epilepsy and autism, and are developing exciting new strategies to treat them. For the brain to function properly, signaling – be it excitatory or inhibitory – must be properly balanced. This is where a nerve cell known as interneurons come i

https://www.stemcellcenter.lu.se/article/restoring-neural-networks-and-understanding-brain-disorders-0 - 2025-12-08

Researchers help in the fight against Covid-19

With the enormous pressure on the Swedish health care system during the ongoing pandemic, researchers from Lund Stem Cell Center are helping battle Covid-19. In response to the increasing number of Covid-19 cases in the south of Sweden, researchers from Lund Stem Cell Center have been working at Lund University Hospital over the holiday period and into the new year, supporting Region Skåne. Johann

https://www.stemcellcenter.lu.se/article/researchers-help-fight-against-covid-19 - 2025-12-08

A new interdisciplinary co-op between researchers, healthcare and industry formed to fight the virus

The fight against COVID-19 continues. In Lund, researchers have been awarded a large Vinnova grant to identify a compound that could be used to prevent viral infection, and thus save lives. The project is a co-operation between preclinical, clinical researchers and a company, an efficient way for creating synergies in research. Project Manager for the study is researcher Sinem Tas, Fellow in Darcy

https://www.stemcellcenter.lu.se/article/new-interdisciplinary-co-op-between-researchers-healthcare-and-industry-formed-fight-virus - 2025-12-08

Emma Hammarlund joins Lund Stem Cell Center

We are very happy to announce that Emma Hammarlund and the Evolution of Stemness Control and Multicellularity research group have joined Lund Stem Cell Center! Emma and her team aim to understand how the rise of animals on Earth relates to the evolution of stemness control, an event we know very little about. Why animals evolved on the Earth remains poorly understood. As does what drove unicellula

https://www.stemcellcenter.lu.se/article/emma-hammarlund-joins-lund-stem-cell-center - 2025-12-08

PhD defence interview – Martina De Santis

PhD student Martina De Santis will be defending her thesis titled ‘Next generation bioengineering of lung tissue for transplantation’ on Friday 19th February 2021. In this interview, Martina tells us about her research in the Lung Bioengineering and Regeneration group and time spent at Lund Stem Cell Center. Can you tell us about your research? -Over three million people die each year and over 60

https://www.stemcellcenter.lu.se/article/phd-defence-interview-martina-de-santis - 2025-12-08

Activation of ancient viruses during brain development causes inflammation

Researchers from Lund Stem Cell Center highlight the importance of controlling viral elements that reside in the genome and how their activation during development may contribute to brain disorders later in life. Around 10% of the human genome is composed of DNA sequences originating from viruses that infected our ancestors throughout the millions of years of our evolution. Under normal conditions

https://www.stemcellcenter.lu.se/article/activation-ancient-viruses-during-brain-development-causes-inflammation - 2025-12-08

Regulation of RNA splicing reveals unique clinical features of aggressive breast cancers

Researchers from Lund University in Sweden have identified a new layer of gene regulation mediated by changes in ribonucleic acid metabolism downstream of major oncogenes. This study, published now in the Molecular Cell journal, explains aggressive clinical features observed in triple negative breast cancers. A collaborative study between Lund Stem Cell Center (LSCC) and Lund University Cancer Cen

https://www.stemcellcenter.lu.se/article/regulation-rna-splicing-reveals-unique-clinical-features-aggressive-breast-cancers - 2025-12-08

PhD defence interview - Shelby Shrigley

During her PhD studies Shelby Shrigley has been exploring patient-specific cell replacement therapy for Parkinson's disease. Defending her PhD thesis on March 12th, here Shelby tells us about her research within the Developmental and Regenerative Neurobiology research group led by Prof. Malin Parmar and her time spent at Lund Stem Cell Center. Can you tell us about your PhD research? The main focu

https://www.stemcellcenter.lu.se/article/phd-defence-interview-shelby-shrigley - 2025-12-08

New method for developing antibody-based drugs

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the genetic scissors CRISPR-Cas9, that facilitates antibody development. The discovery is published in Nature Communications. Antibody drugs are the fastest growing class of drug, and several therapeu

https://www.stemcellcenter.lu.se/article/new-method-developing-antibody-based-drugs - 2025-12-08

New model of human airways speeds up the battle against Covid-19

The fight against COVID-19 continues. In Lund, researchers are working to identify a compound that could be used to prevent viral infection, and thus save lives. “This model that has been developed with our collaborators will fill an important gap for current and future drug screening efforts for the upper or lower airways using human airway cells”, says Sinem Tas, associate researcher. The most r

https://www.stemcellcenter.lu.se/article/new-model-human-airways-speeds-battle-against-covid-19 - 2025-12-08

Welcome two new Principal Investigators to Lund Stem Cell Center

Principal Investigators Daniella Ottosson and Charlotta Böiers have been accepted to join Lund Stem Cell Center.A warm welcome to the Ottosson and Böiers groups. To learn more about their research, the following Stem Cell Talks have been scheduled: Wednesday 25th September: Principal Investigator Daniella Ottosson. Details here.Wednesday 23rd October: Principal Investigator Charlotta Böiers. Detai

https://www.stemcellcenter.lu.se/article/welcome-two-new-principal-investigators-lund-stem-cell-center - 2025-12-08

Tailored therapy for chronic myeloid leukaemia

Chronic myeloid leukaemia (CML) is a slowly progressing form of blood cancer that attacks the blood-forming cells in the bone marrow. The condition requires lifelong treatment that can cause severe side effects. Rebecca Warfvinge maps stem cells in patients in the hope of identifying predictive markers for how the patient will react to therapy. She has now received an award of USD 20,000 from the

https://www.stemcellcenter.lu.se/article/tailored-therapy-chronic-myeloid-leukaemia - 2025-12-08

Cancerfonden supports research into the role of RNA modification in cancer development

The Swedish Cancer Foundation, Cancerfonden, has announced the researchers it will be supporting in its most recent round of funding and Lund Stem Cell Center was especially successful, with seven scientists awarded a total of almost 30 million SEK. Cristian Bellodi, a research team leader from the Division of Molecular Hematology, was awarded 12 million SEK - the largest grant to any researcher a

https://www.stemcellcenter.lu.se/article/cancerfonden-supports-research-role-rna-modification-cancer-development - 2025-12-08

Filipe Pereira awarded European Research Council Consolidator Grant

Today the European Research Council (ERC) announced the winners of its latest Consolidator Grant competition and Filipe Pereira, group leader in the Department of Laboratory Medicine, was one of the researchers awarded this highly competitive grant. One of 89 researchers selected from a total of 707 applicants in the area of Life Sciences, Filipe will be awarded 21 million SEK over five years. The

https://www.stemcellcenter.lu.se/article/filipe-pereira-awarded-european-research-council-consolidator-grant-0 - 2025-12-08

How self-reactive immune cells are allowed to develop

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive – they produce not only antibodies against foreign substances, but also against the body’s own substances, and it is unclear why the immune system allows for the devel

https://www.stemcellcenter.lu.se/article/how-self-reactive-immune-cells-are-allowed-develop - 2025-12-08

How do dementia diseases affect our brains?

By Pia [dot] romare [at] fsi [dot] lu [dot] se (Pia Romare) - published on 23 August 2018“We must understand the ageing process itself in order to help people with conditions such as Alzheimer’s and dementia, and to possibly enable us to prevent these diseases from arising”, says Henrik Ahlenius of the Stem Cell Centre at Lund University. His aim is to develop an experimental model for human nerve

https://www.stemcellcenter.lu.se/article/how-do-dementia-diseases-affect-our-brains - 2025-12-08

Prestigious scientific prize awarded to Director of Lund Stem Cell Center

Zaal Kokaia, Professor within the Department of Clinical Sciences and Director of Lund Stem Cell Center, has been awarded Georgia’s most prestigious scientific prize - the National Prize in Science.  The award comes as a result of his outstanding contribution to world class scientific research and was presented to Prof. Kokaia at a ceremony in the Presidential Palace, Tbilisi, by the Georgian Pres

https://www.stemcellcenter.lu.se/article/prestigious-scientific-prize-awarded-director-lund-stem-cell-center - 2025-12-08